Reflecting on the challenges posed by inequality and regional inequality in Mexico demands a systemic, multidisciplinary and multilevel approach. The reconceptualization of security provides a useful starting point. The reconceptualization of security results from the transatlantic security dispute. On the one hand, we find the “narrow security” standpoint, centred on military and political security, typical of Cold War Geopolitics; which has been re-enforced, once again, following the war on terrorism since 09-11. On the other hand, we find the reconceptualized security outlook typical of the post-Cold War Era of globalization and risk society in the Anthropocene, and embraced by European and Asian countries, putting forward the widening, deepening.